PDB Information

PDB4WPF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Minor Structural Change to Tertiary Sulfonamide RORc Ligands Led to Opposite Mechanisms of Action.
Rene, O., Fauber, B.P., de Leon Boenig, G., Burton, B., Eidenschenk, C., Everett, C., Gobbi, A., Hymowitz, S.G., Johnson, A.R., Kiefer, J.R., Liimatta, M., Lockey, P., Norman, M., Ouyang, W., Wallweber, H.A., Wong, H.
Acs Med.Chem.Lett.
HeaderTranscription
Released2014-10-18
Resolution2.200
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Rejected
D 29 Jun, 2015 Chopped
E 29 Jun, 2015 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4wpfA00 22 Jul, 2015 1.10.565.10 Assigned
4wpfD00 20 Jul, 2015 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma