PDB 4uyf

PDB Links
Overview

PDB Information

PDB	4UYF
Method	X-RAY DIFFRACTION
Host Organism	ESCHERICHIA COLI
Gene Source	HOMO SAPIENS
Primary Citation	The Discovery of I-Bet726 (Gsk1324726A), a Potent Tetrahydroquinoline Apoa1 Up-Regulator and Selective Bet Bromodomain Inhibitor. Gosmini, R., Nguyen, V.L., Toum, J., Simon, C., Brusq, J.M., Krysa, G., Mirguet, O., Riou-Eymard, A.M., Boursier, E.V., Trottet, L., Bamborough, P., Clark, H., Chung, C.W., Cutler, L., Demont, E.H., Kaur, R., Lewis, A.J., Schilling, M.B., Soden, P.E., Taylor, S., Walker, A.L., Walker, M.D., Prinjha, R.K., Nicodeme, E. J.Med.Chem.
Header	Transcription
Released	2014-08-31
Resolution	1.600
CATH Insert Date	19 Oct, 2014

PDB Images (7)

Image of CATH 4uyf

4uyf

PDB 4uyf

Image of CATH 4uyfA

4uyfA

PDB Chain 4uyfA

Image of CATH 4uyfB

4uyfB

PDB Chain 4uyfB

Image of CATH 4uyfC

4uyfC

PDB Chain 4uyfC

Image of CATH 4uyfA00

4uyfA00

CATH Domain 4uyfA00

Image of CATH 4uyfB00

4uyfB00

CATH Domain 4uyfB00

Image of CATH 4uyfC00

4uyfC00

CATH Domain 4uyfC00

PDB Prints

PDB Chains (3)

Chain ID	Date inserted into CATH	CATH Status
A	20 Oct, 2014	Chopped
B	20 Oct, 2014	Chopped
C	20 Oct, 2014	Chopped

CATH Domains (3)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4uyfA00	21 Oct, 2014	1.20.920.10	Assigned
4uyfB00	21 Oct, 2014	1.20.920.10	Assigned
4uyfC00	21 Oct, 2014	1.20.920.10	Assigned

UniProtKB Entries (3)

Accession	Gene ID	Taxon	Description
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2
P25440	BRD2_HUMAN	Homo sapiens	Bromodomain-containing protein 2