PDB 4us0

PDB Information

PDB4US0
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHOMO SAPIENS
Primary Citation
Small Molecule Binding Sites on the Ras:SOS Complex Can be Exploited for Inhibition of Ras Activation.
Winter, J., Anderson, M., Blades, K., Chresta, C., Embrey, K.J., Fairley, G., Faulder, P., Finlay, M.R.V., Kettle, J.G., Nowak, T., Overman, R., Patel, S.J., Perkins, P., Spadola, L., Tart, J., Tucker, J.A., Wrigley, G.
J.Med.Chem.
HeaderSignaling Protein
Released2014-07-02
Resolution2.170
CATH Insert Date28 Jun, 2015

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
R 29 Jun, 2015 Chopped
S 29 Jun, 2015 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4us0R00 15 Jul, 2015 3.40.50.300 Assigned
4us0S01 15 Jul, 2015 1.20.870.10 Assigned
4us0S02 15 Jul, 2015 1.10.840.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q07889 SOS1_HUMAN Homo sapiens Son of sevenless homolog 1
P01112 RASH_HUMAN Homo sapiens GTPase HRas
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