PDB Information

PDB4U5W
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1
Primary Citation
Interaction with the Src Homology (SH3-SH2) Region of the Src-family Kinase Hck Structures the HIV-1 Nef Dimer for Kinase Activation and Effector Recruitment.
Alvarado, J.J., Tarafdar, S., Yeh, J.I., Smithgall, T.E.
J.Biol.Chem.
HeaderViral Protein/Transferase
Released2014-07-25
Resolution1.860
CATH Insert Date24 Aug, 2014

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 25 Aug, 2014 Chopped
B 25 Aug, 2014 Holding pen
C 25 Aug, 2014 Chopped
D 25 Aug, 2014 Domchop review

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4u5wA00 29 Aug, 2014 3.30.62.10 Assigned
4u5wC00 29 Aug, 2014 3.30.62.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P03407 NEF_HV1A2 HIV-1 M:B_ARV2/SF2 Protein Nef
P08631 HCK_HUMAN Homo sapiens Tyrosine-protein kinase HCK
P03407 NEF_HV1A2 HIV-1 M:B_ARV2/SF2 Protein Nef
P08631 HCK_HUMAN Homo sapiens Tyrosine-protein kinase HCK