PDB 4u44

PDB Links
Overview

PDB Information

PDB	4U44
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors. Wang, L., Stanley, M., Boggs, J.W., Crawford, T.D., Bravo, B.J., Giannetti, A.M., Harris, S.F., Magnuson, S.R., Nonomiya, J., Schmidt, S., Wu, P., Ye, W., Gould, S.E., Murray, L.J., Ndubaku, C.O., Chen, H. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2014-07-23
Resolution	2.430
CATH Insert Date	14 Sep, 2014

PDB Images (7)

Image of CATH 4u44

4u44

PDB 4u44

Image of CATH 4u44A

4u44A

PDB Chain 4u44A

Image of CATH 4u44B

4u44B

PDB Chain 4u44B

Image of CATH 4u44A01

4u44A01

CATH Domain 4u44A01

Image of CATH 4u44A02

4u44A02

CATH Domain 4u44A02

Image of CATH 4u44B01

4u44B01

CATH Domain 4u44B01

Image of CATH 4u44B02

4u44B02

CATH Domain 4u44B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	15 Sep, 2014	Chopped
B	15 Sep, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4u44A01	16 Sep, 2014	3.30.200.20	Assigned
4u44A02	16 Sep, 2014	1.10.510.10	Assigned
4u44B01	16 Sep, 2014	3.30.200.20	Assigned
4u44B02	16 Sep, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O95819	M4K4_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4
O95819	M4K4_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase kinase 4