PDB 4u0i

PDB Information

PDB4U0I
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Ponatinib Inhibits Polyclonal Drug-Resistant KIT Oncoproteins and Shows Therapeutic Potential in Heavily Pretreated Gastrointestinal Stromal Tumor (GIST) Patients.
Garner, A.P., Gozgit, J.M., Anjum, R., Vodala, S., Schrock, A., Zhou, T., Serrano, C., Eilers, G., Zhu, M., Ketzer, J., Wardwell, S., Ning, Y., Song, Y., Kohlmann, A., Wang, F., Clackson, T., Heinrich, M.C., Fletcher, J.A., Bauer, S., Rivera, V.M.
Clin.Cancer Res.
HeaderTransferase/Transferase Inhibitor
Released2014-07-11
Resolution2.000
CATH Insert Date19 Oct, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 20 Oct, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4u0iA01 21 Oct, 2014 3.30.200.20 Assigned
4u0iA02 21 Oct, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P10721 KIT_HUMAN Homo sapiens Mast/stem cell growth factor receptor Kit
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