PDB 4tww
PDB Information
| PDB | 4TWW |
| Method | X-RAY DIFFRACTION |
| Host Organism | Escherichia coli BL21(DE3) |
| Gene Source | Human SARS coronavirus |
| Primary Citation | Fused-ring structure of decahydroisoquinolin as a novel scaffold for SARS 3CL protease inhibitors
Bioorg.Med.Chem.
|
| Header | Hydrolase/Hydrolase Inhibitor |
| Released | 2014-07-02 |
| Resolution | 2.420 |
| CATH Insert Date | 28 Jun, 2015 |
PDB Images (9)
PDB Prints
PDB Chains (2)
| Chain ID | Date inserted into CATH | CATH Status |
|---|---|---|
| A | 29 Jun, 2015 | Chopped |
| B | 29 Jun, 2015 | Chopped |
CATH Domains (6)
| Domain ID | Date inserted into CATH | Superfamily | CATH Status |
|---|---|---|---|
| 4twwA01 | 15 Jul, 2015 | 2.40.10.10 | Assigned |
| 4twwA02 | 15 Jul, 2015 | 2.40.10.10 | Assigned |
| 4twwA03 | 15 Jul, 2015 | 1.10.1840.10 | Assigned |
| 4twwB01 | 15 Jul, 2015 | 2.40.10.10 | Assigned |
| 4twwB02 | 15 Jul, 2015 | 2.40.10.10 | Assigned |
| 4twwB03 | 15 Jul, 2015 | 1.10.1840.10 | Assigned |
UniProtKB Entries (2)
| Accession | Gene ID | Taxon | Description |
|---|---|---|---|
| P0C6U8 | R1A_CVHSA | Severe acute respiratory syndrome-related coronavirus | Replicase polyprotein 1a |
| P0C6U8 | R1A_CVHSA | Severe acute respiratory syndrome-related coronavirus | Replicase polyprotein 1a |
