PDB 4tv9

PDB Information

PDB4TV9
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceRattus norvegicus
Primary Citation
A new tubulin-binding site and pharmacophore for microtubule-destabilizing anticancer drugs.
Prota, A.E., Bargsten, K., Diaz, J.F., Marsh, M., Cuevas, C., Liniger, M., Neuhaus, C., Andreu, J.M., Altmann, K.H., Steinmetz, M.O.
Proc.Natl.Acad.Sci.USA
HeaderCell Cycle
Released2014-06-26
Resolution2.000
CATH Insert Date14 Sep, 2014

PDB Images (23)

PDB Prints

PDB Chains (6)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped
C 15 Sep, 2014 Chopped
D 15 Sep, 2014 Chopped
E 15 Sep, 2014 Chopped
F 15 Sep, 2014 Chopped

CATH Domains (16)

Domain ID Date inserted into CATH Superfamily CATH Status
4tv9A01 16 Sep, 2014 3.40.50.1440 Assigned
4tv9A02 16 Sep, 2014 3.30.1330.20 Assigned
4tv9A03 16 Sep, 2014 1.10.287.600 Assigned
4tv9B01 16 Sep, 2014 3.40.50.1440 Assigned
4tv9B02 16 Sep, 2014 3.30.1330.20 Assigned
4tv9B03 16 Sep, 2014 1.10.287.600 Assigned
4tv9C01 16 Sep, 2014 3.40.50.1440 Assigned
4tv9C02 16 Sep, 2014 3.30.1330.20 Assigned
4tv9C03 16 Sep, 2014 1.10.287.600 Assigned
4tv9D01 16 Sep, 2014 3.40.50.1440 Assigned
4tv9D02 16 Sep, 2014 3.30.1330.20 Assigned
4tv9D03 16 Sep, 2014 1.10.287.600 Assigned
4tv9E01 16 Sep, 2014 6.10.280.30 Assigned
4tv9F01 16 Sep, 2014 3.40.50.11480 Assigned
4tv9F02 16 Sep, 2014 3.30.470.20 Assigned
4tv9F03 16 Sep, 2014 3.30.1490.20 Assigned

UniProtKB Entries (6)

Accession Gene ID Taxon Description
E1BQ43 E1BQ43_CHICK Gallus gallus Uncharacterized protein
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
P81947 TBA1B_BOVIN Bos taurus Tubulin alpha-1B chain
P63043 STMN4_RAT Rattus norvegicus Stathmin-4
Q6B856 TBB2B_BOVIN Bos taurus Tubulin beta-2B chain