PDB 4tmr

PDB Information

PDB4TMR
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium vivax
Primary Citation
Inhibitors of Plasmodial Serine Hydroxymethyltransferase (SHMT): Cocrystal Structures of Pyrazolopyrans with Potent Blood- and Liver-Stage Activities.
Witschel, M.C., Rottmann, M., Schwab, A., Leartsakulpanich, U., Chitnumsub, P., Seet, M., Tonazzi, S., Schwertz, G., Stelzer, F., Mietzner, T., McNamara, C., Thater, F., Freymond, C., Jaruwat, A., Pinthong, C., Riangrungroj, P., Oufir, M., Hamburger, M., Maser, P., Sanz-Alonso, L.M., Charman, S., Wittlin, S., Yuthavong, Y., Chaiyen, P., Diederich, F.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-06-02
Resolution2.700
CATH Insert Date28 Jun, 2015

PDB Images (10)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4tmrA01 13 Jul, 2015 3.90.1150.10 Assigned
4tmrA02 13 Jul, 2015 3.40.640.10 Assigned
4tmrB01 15 Jul, 2015 3.90.1150.10 Assigned
4tmrB02 15 Jul, 2015 3.40.640.10 Assigned
4tmrC01 15 Jul, 2015 3.90.1150.10 Assigned
4tmrC02 15 Jul, 2015 3.40.640.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
A5K8L9 A5K8L9_PLAVS Plasmodium vivax Sal-1 Serine hydroxymethyltransferase, putative
A5K8L9 A5K8L9_PLAVS Plasmodium vivax Sal-1 Serine hydroxymethyltransferase, putative
A5K8L9 A5K8L9_PLAVS Plasmodium vivax Sal-1 Serine hydroxymethyltransferase, putative