PDB Information

PDB4RWK
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Illuminating the Molecular Mechanisms of Tyrosine Kinase Inhibitor Resistance for the FGFR1 Gatekeeper Mutation: The Achilles' Heel of Targeted Therapy.
Sohl, C.D., Ryan, M.R., Luo, B., Frey, K.M., Anderson, K.S.
Acs Chem.Biol.
HeaderTransferase/Transferase Inhibitor
Released2014-12-04
Resolution2.980
CATH Insert Date28 Jun, 2015

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4rwkA01 10 Jul, 2015 3.30.200.20 Assigned
4rwkA02 10 Jul, 2015 1.10.510.10 Assigned
4rwkB01 10 Jul, 2015 3.30.200.20 Assigned
4rwkB02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1
P11362 FGFR1_HUMAN Homo sapiens Fibroblast growth factor receptor 1