PDB 4rt7

PDB Information

PDB4RT7
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Characterizing and Overriding the Structural Mechanism of the Quizartinib-Resistant FLT3 "Gatekeeper" F691L Mutation with PLX3397.
Smith, C.C., Zhang, C., Lin, K.C., Lasater, E.A., Zhang, Y., Massi, E., Damon, L.E., Pendleton, M., Bashir, A., Sebra, R., Perl, A., Kasarskis, A., Shellooe, R., Tsang, G., Carias, H., Powell, B., Burton, E.A., Matusow, B., Zhang, J., Spevak, W., Ibrahim, P.N., Le, M.H., Hsu, H.H., Habets, G., West, B.L., Bollag, G., Shah, N.P.
Cancer Discov
HeaderTransferase/Transferase Inhibitor
Released2014-11-13
Resolution3.100
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4rt7A01 10 Jul, 2015 3.30.200.20 Assigned
4rt7A02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P36888 FLT3_HUMAN Homo sapiens Receptor-type tyrosine-protein kinase FLT3
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