PDB 4rj3

PDB Information

PDB4RJ3
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of Selective and Noncovalent Diaminopyrimidine-Based Inhibitors of Epidermal Growth Factor Receptor Containing the T790M Resistance Mutation.
Hanan, E.J., Eigenbrot, C., Bryan, M.C., Burdick, D.J., Chan, B.K., Chen, Y., Dotson, J., Heald, R.A., Jackson, P.S., La, H., Lainchbury, M.D., Malek, S., Purkey, H.E., Schaefer, G., Schmidt, S., Seward, E.M., Sideris, S., Tam, C., Wang, S., Yeap, S.K., Yen, I., Yin, J., Yu, C., Zilberleyb, I., Heffron, T.P.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-10-08
Resolution1.630
CATH Insert Date07 Dec, 2014

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 08 Dec, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4rj3A01 29 Dec, 2014 3.30.200.20 Assigned
4rj3A02 29 Dec, 2014 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2