PDB Information

PDB4RHX
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
First Crystal Structures of Mycobacterium tuberculosis 6-Oxopurine Phosphoribosyltransferase: Complexes with GMP and Pyrophosphate and with Acyclic Nucleoside Phosphonates Whose Prodrugs Have Antituberculosis Activity.
Eng, W.S., Hockova, D., Spacek, P., Janeba, Z., West, N.P., Woods, K., Naesens, L.M., Keough, D.T., Guddat, L.W.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-10-03
Resolution2.030
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4rhxA00 11 Jul, 2015 3.40.50.2020 Assigned
4rhxB00 10 Jul, 2015 3.40.50.2020 Assigned
4rhxC00 10 Jul, 2015 3.40.50.2020 Assigned
4rhxD00 10 Jul, 2015 3.40.50.2020 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase
P9WHQ9 HPRT_MYCTU Mycobacterium tuberculosis H37Rv Hypoxanthine-guanine phosphoribosyltransferase