PDB 4rce

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Overview

PDB Information

PDB	4RCE
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Lead Optimization and Modulation of hERG Activity in a Series of Aminooxazoline Xanthene beta-Site Amyloid Precursor Protein Cleaving Enzyme (BACE1) Inhibitors. Epstein, O., Bryan, M.C., Cheng, A.C., Derakhchan, K., Dineen, T.A., Hickman, D., Hua, Z., Human, J.B., Kreiman, C., Marx, I.E., Weiss, M.M., Wahl, R.C., Wen, P.H., Whittington, D.A., Wood, S., Zheng, X.M., Fremeau, R.T., White, R.D., Patel, V.F. J.Med.Chem.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-09-15
Resolution	2.400
CATH Insert Date	04 Jan, 2015

PDB Images (4)

Image of CATH 4rce

4rce

PDB 4rce

Image of CATH 4rceA

4rceA

PDB Chain 4rceA

Image of CATH 4rceA01

4rceA01

CATH Domain 4rceA01

Image of CATH 4rceA02

4rceA02

CATH Domain 4rceA02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Jan, 2015	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4rceA01	10 Jan, 2015	2.40.70.10	Assigned
4rceA02	10 Jan, 2015	2.40.70.10	Assigned

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1