PDB Information

PDB4RAO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Aza-acyclic Nucleoside Phosphonates Containing a Second Phosphonate Group As Inhibitors of the Human, Plasmodium falciparum and vivax 6-Oxopurine Phosphoribosyltransferases and Their Prodrugs As Antimalarial Agents.
Keough, D.T., Hockova, D., Janeba, Z., Wang, T.H., Naesens, L., Edstein, M.D., Chavchich, M., Guddat, L.W.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-09-10
Resolution1.870
CATH Insert Date28 Jun, 2015

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped
C 29 Jun, 2015 Chopped
D 29 Jun, 2015 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4raoA00 10 Jul, 2015 3.40.50.2020 Assigned
4raoB00 10 Jul, 2015 3.40.50.2020 Assigned
4raoC00 10 Jul, 2015 3.40.50.2020 Assigned
4raoD00 10 Jul, 2015 3.40.50.2020 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase
P00492 HPRT_HUMAN Homo sapiens Hypoxanthine-guanine phosphoribosyltransferase