PDB 4r93

PDB Links
Overview

PDB Information

PDB	4R93
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of potent iminoheterocycle BACE1 inhibitors. Caldwell, J.P., Mazzola, R.D., Durkin, J., Chen, J., Chen, X., Favreau, L., Kennedy, M., Kuvelkar, R., Lee, J., McHugh, N., McKittrick, B., Orth, P., Stamford, A., Strickland, C., Voigt, J., Wang, L., Zhang, L., Zhang, Q., Zhu, Z. Bioorg.Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-09-03
Resolution	1.710
CATH Insert Date	16 Nov, 2014

PDB Images (7)

Image of CATH 4r93

4r93

PDB 4r93

Image of CATH 4r93A

4r93A

PDB Chain 4r93A

Image of CATH 4r93B

4r93B

PDB Chain 4r93B

Image of CATH 4r93A01

4r93A01

CATH Domain 4r93A01

Image of CATH 4r93A02

4r93A02

CATH Domain 4r93A02

Image of CATH 4r93B01

4r93B01

CATH Domain 4r93B01

Image of CATH 4r93B02

4r93B02

CATH Domain 4r93B02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	17 Nov, 2014	Chopped
B	17 Nov, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4r93A01	19 Nov, 2014	2.40.70.10	Assigned
4r93A02	19 Nov, 2014	2.40.70.10	Assigned
4r93B01	19 Nov, 2014	2.40.70.10	Assigned
4r93B02	19 Nov, 2014	2.40.70.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1
P56817	BACE1_HUMAN	Homo sapiens	Beta-secretase 1