PDB Information

PDB4R7H
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Structure-Guided Blockade of CSF1R Kinase in Tenosynovial Giant-Cell Tumor.
Tap, W.D., Wainberg, Z.A., Anthony, S.P., Ibrahim, P.N., Zhang, C., Healey, J.H., Chmielowski, B., Staddon, A.P., Cohn, A.L., Shapiro, G.I., Keedy, V.L., Singh, A.S., Puzanov, I., Kwak, E.L., Wagner, A.J., Von Hoff, D.D., Weiss, G.J., Ramanathan, R.K., Zhang, J., Habets, G., Zhang, Y., Burton, E.A., Visor, G., Sanftner, L., Severson, P., Nguyen, H., Kim, M.J., Marimuthu, A., Tsang, G., Shellooe, R., Gee, C., West, B.L., Hirth, P., Nolop, K., van de Rijn, M., Hsu, H.H., Peterfy, C., Lin, P.S., Tong-Starksen, S., Bollag, G.
N Engl J Med
HeaderTransferase/Transferase Inhibitor
Released2014-08-27
Resolution2.800
CATH Insert Date30 Aug, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 31 Aug, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4r7hA01 03 Sep, 2015 3.30.200.20 Assigned
4r7hA02 03 Sep, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P07333 CSF1R_HUMAN Homo sapiens Macrophage colony-stimulating factor 1 receptor