PDB 4qws

PDB Links
Overview

PDB Information

PDB	4QWS
Method	X-RAY DIFFRACTION
Host Organism	SACCHAROMYCES CEREVISIAE
Gene Source	Saccharomyces cerevisiae
Primary Citation	Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Huber, E.M., Heinemeyer, W., Groll, M. Structure
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-07-17
Resolution	3.000
CATH Insert Date	28 Jun, 2015

PDB Images (57)

4qws

PDB 4qws

4qwsa

PDB Chain 4qwsa

4qwsA

PDB Chain 4qwsA

4qwsb

PDB Chain 4qwsb

4qwsB

PDB Chain 4qwsB

4qwsC

PDB Chain 4qwsC

4qwsD

PDB Chain 4qwsD

4qwsE

PDB Chain 4qwsE

4qwsF

PDB Chain 4qwsF

4qwsG

PDB Chain 4qwsG

4qwsH

PDB Chain 4qwsH

4qwsI

PDB Chain 4qwsI

4qwsJ

PDB Chain 4qwsJ

4qwsK

PDB Chain 4qwsK

4qwsL

PDB Chain 4qwsL

4qwsM

PDB Chain 4qwsM

4qwsN

PDB Chain 4qwsN

4qwsO

PDB Chain 4qwsO

4qwsP

PDB Chain 4qwsP

4qwsQ

PDB Chain 4qwsQ

4qwsR

PDB Chain 4qwsR

4qwsS

PDB Chain 4qwsS

4qwsT

PDB Chain 4qwsT

4qwsU

PDB Chain 4qwsU

4qwsV

PDB Chain 4qwsV

4qwsW

PDB Chain 4qwsW

4qwsX

PDB Chain 4qwsX

4qwsY

PDB Chain 4qwsY

4qwsZ

PDB Chain 4qwsZ

4qwsa00

CATH Domain 4qwsa00

4qwsA00

CATH Domain 4qwsA00

4qwsb00

CATH Domain 4qwsb00

4qwsB00

CATH Domain 4qwsB00

4qwsC00

CATH Domain 4qwsC00

4qwsD00

CATH Domain 4qwsD00

4qwsE00

CATH Domain 4qwsE00

4qwsF00

CATH Domain 4qwsF00

4qwsG00

CATH Domain 4qwsG00

4qwsH00

CATH Domain 4qwsH00

4qwsI00

CATH Domain 4qwsI00

4qwsJ00

CATH Domain 4qwsJ00

4qwsK00

CATH Domain 4qwsK00

4qwsL00

CATH Domain 4qwsL00

4qwsM00

CATH Domain 4qwsM00

4qwsN00

CATH Domain 4qwsN00

4qwsO00

CATH Domain 4qwsO00

4qwsP00

CATH Domain 4qwsP00

4qwsQ00

CATH Domain 4qwsQ00

4qwsR00

CATH Domain 4qwsR00

4qwsS00

CATH Domain 4qwsS00

4qwsT00

CATH Domain 4qwsT00

4qwsU00

CATH Domain 4qwsU00

4qwsV00

CATH Domain 4qwsV00

4qwsW00

CATH Domain 4qwsW00

4qwsX00

CATH Domain 4qwsX00

4qwsY00

CATH Domain 4qwsY00

4qwsZ00

CATH Domain 4qwsZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	29 Jun, 2015	Chopped
A	29 Jun, 2015	Chopped
b	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
C	29 Jun, 2015	Chopped
D	29 Jun, 2015	Chopped
E	29 Jun, 2015	Chopped
F	29 Jun, 2015	Chopped
G	29 Jun, 2015	Chopped
H	29 Jun, 2015	Chopped
I	29 Jun, 2015	Chopped
J	29 Jun, 2015	Chopped
K	29 Jun, 2015	Chopped
L	29 Jun, 2015	Chopped
M	29 Jun, 2015	Chopped
N	29 Jun, 2015	Chopped
O	29 Jun, 2015	Chopped
P	29 Jun, 2015	Chopped
Q	29 Jun, 2015	Chopped
R	29 Jun, 2015	Chopped
S	29 Jun, 2015	Chopped
T	29 Jun, 2015	Chopped
U	29 Jun, 2015	Chopped
V	29 Jun, 2015	Chopped
W	29 Jun, 2015	Chopped
X	29 Jun, 2015	Chopped
Y	29 Jun, 2015	Chopped
Z	29 Jun, 2015	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4qwsa00	10 Jul, 2015	3.60.20.10	Assigned
4qwsA00	10 Jul, 2015	3.60.20.10	Assigned
4qwsb00	10 Jul, 2015	3.60.20.10	Assigned
4qwsB00	10 Jul, 2015	3.60.20.10	Assigned
4qwsC00	10 Jul, 2015	3.60.20.10	Assigned
4qwsD00	10 Jul, 2015	3.60.20.10	Assigned
4qwsE00	10 Jul, 2015	3.60.20.10	Assigned
4qwsF00	10 Jul, 2015	3.60.20.10	Assigned
4qwsG00	10 Jul, 2015	3.60.20.10	Assigned
4qwsH00	10 Jul, 2015	3.60.20.10	Assigned
4qwsI00	10 Jul, 2015	3.60.20.10	Assigned
4qwsJ00	10 Jul, 2015	3.60.20.10	Assigned
4qwsK00	10 Jul, 2015	3.60.20.10	Assigned
4qwsL00	10 Jul, 2015	3.60.20.10	Assigned
4qwsM00	10 Jul, 2015	3.60.20.10	Assigned
4qwsN00	10 Jul, 2015	3.60.20.10	Assigned
4qwsO00	10 Jul, 2015	3.60.20.10	Assigned
4qwsP00	10 Jul, 2015	3.60.20.10	Assigned
4qwsQ00	10 Jul, 2015	3.60.20.10	Assigned
4qwsR00	10 Jul, 2015	3.60.20.10	Assigned
4qwsS00	10 Jul, 2015	3.60.20.10	Assigned
4qwsT00	10 Jul, 2015	3.60.20.10	Assigned
4qwsU00	10 Jul, 2015	3.60.20.10	Assigned
4qwsV00	10 Jul, 2015	3.60.20.10	Assigned
4qwsW00	10 Jul, 2015	3.60.20.10	Assigned
4qwsX00	10 Jul, 2015	3.60.20.10	Assigned
4qwsY00	10 Jul, 2015	3.60.20.10	Assigned
4qwsZ00	10 Jul, 2015	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5