PDB 4qwk

PDB Links
Overview

PDB Information

PDB	4QWK
Method	X-RAY DIFFRACTION
Host Organism	SACCHAROMYCES CEREVISIAE
Gene Source	Saccharomyces cerevisiae
Primary Citation	Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Huber, E.M., Heinemeyer, W., Groll, M. Structure
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-07-16
Resolution	2.800
CATH Insert Date	28 Jun, 2015

PDB Images (57)

4qwk

PDB 4qwk

4qwka

PDB Chain 4qwka

4qwkA

PDB Chain 4qwkA

4qwkb

PDB Chain 4qwkb

4qwkB

PDB Chain 4qwkB

4qwkC

PDB Chain 4qwkC

4qwkD

PDB Chain 4qwkD

4qwkE

PDB Chain 4qwkE

4qwkF

PDB Chain 4qwkF

4qwkG

PDB Chain 4qwkG

4qwkH

PDB Chain 4qwkH

4qwkI

PDB Chain 4qwkI

4qwkJ

PDB Chain 4qwkJ

4qwkK

PDB Chain 4qwkK

4qwkL

PDB Chain 4qwkL

4qwkM

PDB Chain 4qwkM

4qwkN

PDB Chain 4qwkN

4qwkO

PDB Chain 4qwkO

4qwkP

PDB Chain 4qwkP

4qwkQ

PDB Chain 4qwkQ

4qwkR

PDB Chain 4qwkR

4qwkS

PDB Chain 4qwkS

4qwkT

PDB Chain 4qwkT

4qwkU

PDB Chain 4qwkU

4qwkV

PDB Chain 4qwkV

4qwkW

PDB Chain 4qwkW

4qwkX

PDB Chain 4qwkX

4qwkY

PDB Chain 4qwkY

4qwkZ

PDB Chain 4qwkZ

4qwka00

CATH Domain 4qwka00

4qwkA00

CATH Domain 4qwkA00

4qwkb00

CATH Domain 4qwkb00

4qwkB00

CATH Domain 4qwkB00

4qwkC00

CATH Domain 4qwkC00

4qwkD00

CATH Domain 4qwkD00

4qwkE00

CATH Domain 4qwkE00

4qwkF00

CATH Domain 4qwkF00

4qwkG00

CATH Domain 4qwkG00

4qwkH00

CATH Domain 4qwkH00

4qwkI00

CATH Domain 4qwkI00

4qwkJ00

CATH Domain 4qwkJ00

4qwkK00

CATH Domain 4qwkK00

4qwkL00

CATH Domain 4qwkL00

4qwkM00

CATH Domain 4qwkM00

4qwkN00

CATH Domain 4qwkN00

4qwkO00

CATH Domain 4qwkO00

4qwkP00

CATH Domain 4qwkP00

4qwkQ00

CATH Domain 4qwkQ00

4qwkR00

CATH Domain 4qwkR00

4qwkS00

CATH Domain 4qwkS00

4qwkT00

CATH Domain 4qwkT00

4qwkU00

CATH Domain 4qwkU00

4qwkV00

CATH Domain 4qwkV00

4qwkW00

CATH Domain 4qwkW00

4qwkX00

CATH Domain 4qwkX00

4qwkY00

CATH Domain 4qwkY00

4qwkZ00

CATH Domain 4qwkZ00

PDB Prints

PDB Chains (28)

Chain ID	Date inserted into CATH	CATH Status
a	29 Jun, 2015	Chopped
A	29 Jun, 2015	Chopped
b	29 Jun, 2015	Chopped
B	29 Jun, 2015	Chopped
C	29 Jun, 2015	Chopped
D	29 Jun, 2015	Chopped
E	29 Jun, 2015	Chopped
F	29 Jun, 2015	Chopped
G	29 Jun, 2015	Chopped
H	29 Jun, 2015	Chopped
I	29 Jun, 2015	Chopped
J	29 Jun, 2015	Chopped
K	29 Jun, 2015	Chopped
L	29 Jun, 2015	Chopped
M	29 Jun, 2015	Chopped
N	29 Jun, 2015	Chopped
O	29 Jun, 2015	Chopped
P	29 Jun, 2015	Chopped
Q	29 Jun, 2015	Chopped
R	29 Jun, 2015	Chopped
S	29 Jun, 2015	Chopped
T	29 Jun, 2015	Chopped
U	29 Jun, 2015	Chopped
V	29 Jun, 2015	Chopped
W	29 Jun, 2015	Chopped
X	29 Jun, 2015	Chopped
Y	29 Jun, 2015	Chopped
Z	29 Jun, 2015	Chopped

CATH Domains (28)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4qwka00	10 Jul, 2015	3.60.20.10	Assigned
4qwkA00	10 Jul, 2015	3.60.20.10	Assigned
4qwkb00	10 Jul, 2015	3.60.20.10	Assigned
4qwkB00	10 Jul, 2015	3.60.20.10	Assigned
4qwkC00	10 Jul, 2015	3.60.20.10	Assigned
4qwkD00	10 Jul, 2015	3.60.20.10	Assigned
4qwkE00	10 Jul, 2015	3.60.20.10	Assigned
4qwkF00	10 Jul, 2015	3.60.20.10	Assigned
4qwkG00	10 Jul, 2015	3.60.20.10	Assigned
4qwkH00	10 Jul, 2015	3.60.20.10	Assigned
4qwkI00	10 Jul, 2015	3.60.20.10	Assigned
4qwkJ00	10 Jul, 2015	3.60.20.10	Assigned
4qwkK00	10 Jul, 2015	3.60.20.10	Assigned
4qwkL00	10 Jul, 2015	3.60.20.10	Assigned
4qwkM00	10 Jul, 2015	3.60.20.10	Assigned
4qwkN00	10 Jul, 2015	3.60.20.10	Assigned
4qwkO00	10 Jul, 2015	3.60.20.10	Assigned
4qwkP00	10 Jul, 2015	3.60.20.10	Assigned
4qwkQ00	10 Jul, 2015	3.60.20.10	Assigned
4qwkR00	10 Jul, 2015	3.60.20.10	Assigned
4qwkS00	10 Jul, 2015	3.60.20.10	Assigned
4qwkT00	10 Jul, 2015	3.60.20.10	Assigned
4qwkU00	10 Jul, 2015	3.60.20.10	Assigned
4qwkV00	10 Jul, 2015	3.60.20.10	Assigned
4qwkW00	10 Jul, 2015	3.60.20.10	Assigned
4qwkX00	10 Jul, 2015	3.60.20.10	Assigned
4qwkY00	10 Jul, 2015	3.60.20.10	Assigned
4qwkZ00	10 Jul, 2015	3.60.20.10	Assigned

UniProtKB Entries (28)

Accession	Gene ID	Taxon	Description
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P23639	PSA2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-2
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P23638	PSA3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-3
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5
P23724	PSB6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-6
P21243	PSA1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-1
P22141	PSB4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-4
P21242	PSA7_YEAST	Saccharomyces cerevisiae S288C	Probable proteasome subunit alpha type-7
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P38624	PSB1_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-1
P32379	PSA5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-5
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P40303	PSA4_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-4
P25451	PSB3_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-3
P30657	PSB7_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-7
P25043	PSB2_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-2
P40302	PSA6_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit alpha type-6
P30656	PSB5_YEAST	Saccharomyces cerevisiae S288C	Proteasome subunit beta type-5