PDB 4qd6

PDB Information

PDB4QD6
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Design, synthesis and structure-activity relationships of a novel class of sulfonylpyridine inhibitors of Interleukin-2 inducible T-cell kinase (ITK).
Trani, G., Barker, J.J., Bromidge, S.M., Brookfield, F.A., Burch, J.D., Chen, Y., Eigenbrot, C., Heifetz, A., Ismaili, M.H., Johnson, A., Krulle, T.M., MacKinnon, C.H., Maghames, R., McEwan, P.A., Montalbetti, C.A., Ortwine, D.F., Perez-Fuertes, Y., Vaidya, D.G., Wang, X., Zarrin, A.A., Pei, Z.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-05-13
Resolution2.450
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4qd6A00 10 Jul, 2015 1.10.510.10 Assigned
4qd6B00 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK
Q08881 ITK_HUMAN Homo sapiens Tyrosine-protein kinase ITK/TSK