PDB 4q1b

PDB Information

PDB4Q1B
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-guided development of deoxycytidine kinase inhibitors with nanomolar affinity and improved metabolic stability.
Nomme, J., Li, Z., Gipson, R.M., Wang, J., Armijo, A.L., Le, T., Poddar, S., Smith, T., Santarsiero, B.D., Nguyen, H.A., Czernin, J., Alexandrova, A.N., Jung, M.E., Radu, C.G., Lavie, A.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2014-04-03
Resolution2.150
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4q1bA00 10 Jul, 2015 3.40.50.300 Assigned
4q1bB00 10 Jul, 2015 3.40.50.300 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P27707 DCK_HUMAN Homo sapiens Deoxycytidine kinase
P27707 DCK_HUMAN Homo sapiens Deoxycytidine kinase