PDB 4puz

PDB Links
Overview

PDB Information

PDB	4PUZ
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of GS-9973, a Selective and Orally Efficacious Inhibitor of Spleen Tyrosine Kinase. Currie, K.S., Kropf, J.E., Lee, T., Blomgren, P., Xu, J., Zhao, Z., Gallion, S., Whitney, J.A., Maclin, D., Lansdon, E.B., Maciejewski, P., Rossi, A.M., Rong, H., Macaluso, J., Barbosa, J., Di Paolo, J.A., Mitchell, S.A. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2014-03-14
Resolution	2.090
CATH Insert Date	27 Apr, 2014

PDB Images (7)

Image of CATH 4puz

4puz

PDB 4puz

Image of CATH 4puzA

4puzA

PDB Chain 4puzA

Image of CATH 4puzB

4puzB

PDB Chain 4puzB

Image of CATH 4puzA01

4puzA01

CATH Domain 4puzA01

Image of CATH 4puzA02

4puzA02

CATH Domain 4puzA02

Image of CATH 4puzB01

4puzB01

CATH Domain 4puzB01

Image of CATH 4puzB02

4puzB02

CATH Domain 4puzB02

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	28 Apr, 2014	Chopped
B	28 Apr, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4puzA01	03 May, 2014	3.30.200.20	Assigned
4puzA02	03 May, 2014	1.10.510.10	Assigned
4puzB01	03 May, 2014	3.30.200.20	Assigned
4puzB02	03 May, 2014	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P43405	KSYK_HUMAN	Homo sapiens	Tyrosine-protein kinase SYK
P43405	KSYK_HUMAN	Homo sapiens	Tyrosine-protein kinase SYK