PDB 4p1r

PDB Links
Overview

PDB Information

PDB	4P1R
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). Hu, E., Andrews, K., Chmait, S., Zhao, X., Davis, C., Miller, S., Hill Della Puppa, G., Dovlatyan, M., Chen, H., Lester-Zeiner, D., Able, J., Biorn, C., Ma, J., Shi, J., Treanor, J., Allen, J.R. Acs Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inbhitor
Released	2014-02-27
Resolution	2.240
CATH Insert Date	10 Aug, 2014

PDB Images (5)

Image of CATH 4p1r

4p1r

PDB 4p1r

Image of CATH 4p1rA

4p1rA

PDB Chain 4p1rA

Image of CATH 4p1rB

4p1rB

PDB Chain 4p1rB

Image of CATH 4p1rA00

4p1rA00

CATH Domain 4p1rA00

Image of CATH 4p1rB00

4p1rB00

CATH Domain 4p1rB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	11 Aug, 2014	Chopped
B	11 Aug, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4p1rA00	19 Aug, 2014	1.10.1300.10	Assigned
4p1rB00	20 Aug, 2014	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A