PDB 4p0n

PDB Links
Overview

PDB Information

PDB	4P0N
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of Novel Imidazo[4,5-b]pyridines as Potent and Selective Inhibitors of Phosphodiesterase 10A (PDE10A). Hu, E., Andrews, K., Chmait, S., Zhao, X., Davis, C., Miller, S., Hill Della Puppa, G., Dovlatyan, M., Chen, H., Lester-Zeiner, D., Able, J., Biorn, C., Ma, J., Shi, J., Treanor, J., Allen, J.R. Acs Med.Chem.Lett.
Header	Hydrolase/Hydrolase Inhibitor
Released	2014-02-21
Resolution	2.080
CATH Insert Date	19 Oct, 2014

PDB Images (5)

Image of CATH 4p0n

4p0n

PDB 4p0n

Image of CATH 4p0nA

4p0nA

PDB Chain 4p0nA

Image of CATH 4p0nB

4p0nB

PDB Chain 4p0nB

Image of CATH 4p0nA00

4p0nA00

CATH Domain 4p0nA00

Image of CATH 4p0nB00

4p0nB00

CATH Domain 4p0nB00

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	20 Oct, 2014	Chopped
B	20 Oct, 2014	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4p0nA00	21 Oct, 2014	1.10.1300.10	Assigned
4p0nB00	21 Oct, 2014	1.10.1300.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A
Q9Y233	PDE10_HUMAN	Homo sapiens	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A