PDB 4otf

PDB Information

PDB4OTF
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Potent and selective Bruton's tyrosine kinase inhibitors: Discovery of GDC-0834.
Young, W.B., Barbosa, J., Blomgren, P., Bremer, M.C., Crawford, J.J., Dambach, D., Gallion, S., Hymowitz, S.G., Kropf, J.E., Lee, S.H., Liu, L., Lubach, J.W., Macaluso, J., Maciejewski, P., Maurer, B., Mitchell, S.A., Ortwine, D.F., Di Paolo, J., Reif, K., Scheerens, H., Schmitt, A., Sowell, C.G., Wang, X., Wong, H., Xiong, J.M., Xu, J., Zhao, Z., Currie, K.S.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2014-02-13
Resolution1.950
CATH Insert Date28 Jun, 2015

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4otfA01 10 Jul, 2015 3.30.200.20 Assigned
4otfA02 10 Jul, 2015 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q06187 BTK_HUMAN Homo sapiens Tyrosine-protein kinase BTK
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