PDB Information

PDB4OIV
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural Basis for Small Molecule NDB (N-Benzyl-N-(3-(tert-butyl)-4-hydroxyphenyl)-2,6-dichloro-4-(dimethylamino) Benzamide) as a Selective Antagonist of Farnesoid X Receptor alpha (FXR alpha ) in Stabilizing the Homodimerization of the Receptor.
Xu, X., Xu, X., Liu, P., Zhu, Z.Y., Chen, J., Fu, H.A., Chen, L.L., Hu, L.H., Shen, X.
J.Biol.Chem.
HeaderNuclear Protein Receptor
Released2014-01-20
Resolution1.700
CATH Insert Date28 Jun, 2015

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 29 Jun, 2015 Chopped
B 29 Jun, 2015 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4oivA00 09 Jul, 2015 1.10.565.10 Assigned
4oivB00 09 Jul, 2015 1.10.565.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q96RI1 NR1H4_HUMAN Homo sapiens Bile acid receptor
Q96RI1 NR1H4_HUMAN Homo sapiens Bile acid receptor