PDB 4nyf

PDB Information

PDB4NYF
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus type 1
Primary Citation
Discovery of BI 224436, a Noncatalytic Site Integrase Inhibitor (NCINI) of HIV-1.
Fader, L.D., Malenfant, E., Parisien, M., Carson, R., Bilodeau, F., Landry, S., Pesant, M., Brochu, C., Morin, S., Chabot, C., Halmos, T., Bousquet, Y., Bailey, M.D., Kawai, S.H., Coulombe, R., LaPlante, S., Jakalian, A., Bhardwaj, P.K., Wernic, D., Schroeder, P., Amad, M., Edwards, P., Garneau, M., Duan, J., Cordingley, M., Bethell, R., Mason, S.W., Bos, M., Bonneau, P., Poupart, M.A., Faucher, A.M., Simoneau, B., Fenwick, C., Yoakim, C., Tsantrizos, Y.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2013-12-10
Resolution1.900
CATH Insert Date06 Jul, 2014

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Jul, 2014 Chopped
B 07 Jul, 2014 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4nyfA00 15 Jul, 2014 3.30.420.10 Assigned
4nyfB00 15 Jul, 2014 3.30.420.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein
P0C6F2 POL_HV1LW Human immunodeficiency virus type 1 lw12.3 isolate Gag-Pol polyprotein