PDB 4nxo

PDB Links
Overview

PDB Information

PDB	4NXO
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice. Deprez-Poulain, R., Hennuyer, N., Bosc, D., Liang, W.G., Enee, E., Marechal, X., Charton, J., Totobenazara, J., Berte, G., Jahklal, J., Verdelet, T., Dumont, J., Dassonneville, S., Woitrain, E., Gauriot, M., Paquet, C., Duplan, I., Hermant, P., Cantrelle, F.X., Sevin, E., Culot, M., Landry, V., Herledan, A., Piveteau, C., Lippens, G., Leroux, F., Tang, W.J., van Endert, P., Staels, B., Deprez, B. Nat Commun
Header	Hydrolase/Hydrolase Inhibitor
Released	2013-12-09
Resolution	2.730
CATH Insert Date	18 Oct, 2015

PDB Images (11)

Image of CATH 4nxo

4nxo

PDB 4nxo

Image of CATH 4nxoA

4nxoA

PDB Chain 4nxoA

Image of CATH 4nxoB

4nxoB

PDB Chain 4nxoB

Image of CATH 4nxoA01

4nxoA01

CATH Domain 4nxoA01

Image of CATH 4nxoA02

4nxoA02

CATH Domain 4nxoA02

Image of CATH 4nxoA03

4nxoA03

CATH Domain 4nxoA03

Image of CATH 4nxoA04

4nxoA04

CATH Domain 4nxoA04

Image of CATH 4nxoB01

4nxoB01

CATH Domain 4nxoB01

Image of CATH 4nxoB02

4nxoB02

CATH Domain 4nxoB02

Image of CATH 4nxoB03

4nxoB03

CATH Domain 4nxoB03

Image of CATH 4nxoB04

4nxoB04

CATH Domain 4nxoB04

PDB Prints

PDB Chains (2)

Chain ID	Date inserted into CATH	CATH Status
A	19 Oct, 2015	Chopped
B	19 Oct, 2015	Chopped

CATH Domains (8)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4nxoA01	01 Nov, 2015	3.30.830.10	Assigned
4nxoA02	01 Nov, 2015	3.30.830.10	Assigned
4nxoA03	01 Nov, 2015	3.30.830.10	Assigned
4nxoA04	01 Nov, 2015	3.30.830.10	Assigned
4nxoB01	31 Oct, 2015	3.30.830.10	Assigned
4nxoB02	31 Oct, 2015	3.30.830.10	Assigned
4nxoB03	31 Oct, 2015	3.30.830.10	Assigned
4nxoB04	31 Oct, 2015	3.30.830.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme
P14735	IDE_HUMAN	Homo sapiens	Insulin-degrading enzyme