PDB 4nie

PDB Information

PDB4NIE
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Discovery of Tertiary Amine and Indole Derivatives as Potent ROR gamma t Inverse Agonists.
Yang, T., Liu, Q., Cheng, Y., Cai, W., Ma, Y., Yang, L., Wu, Q., Orband-Miller, L.A., Zhou, L., Xiang, Z., Huxdorf, M., Zhang, W., Zhang, J., Xiang, J.N., Leung, S., Qiu, Y., Zhong, Z., Elliott, J.D., Lin, X., Wang, Y.
Acs Med.Chem.Lett.
HeaderTranscription/Agonist
Released2013-11-06
Resolution2.010
CATH Insert Date15 Dec, 2013

PDB Images (7)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 16 Dec, 2013 Chopped
B 16 Dec, 2013 Chopped
C 16 Dec, 2013 Rejected
D 16 Dec, 2013 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4nieA00 20 Dec, 2013 1.10.565.10 Assigned
4nieB00 20 Dec, 2013 1.10.565.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
Q15596 NCOA2_HUMAN Homo sapiens Nuclear receptor coactivator 2
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma
P51449 RORG_HUMAN Homo sapiens Nuclear receptor ROR-gamma