PDB 4ncm

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Overview

PDB Information

PDB	4NCM
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Influenza A virus
Primary Citation	Discovery of a Novel, First-in-Class, Orally Bioavailable Azaindole Inhibitor (VX-787) of Influenza PB2. Clark, M.P., Ledeboer, M.W., Davies, I., Byrn, R.A., Jones, S.M., Perola, E., Tsai, A., Jacobs, M., Nti-Addae, K., Bandarage, U.K., Boyd, M.J., Bethiel, R.S., Court, J.J., Deng, H., Duffy, J.P., Dorsch, W.A., Farmer, L.J., Gao, H., Gu, W., Jackson, K., Jacobs, D.H., Kennedy, J.M., Ledford, B., Liang, J., Maltais, F., Murcko, M., Wang, T., Wannamaker, M.W., Bennett, H.B., Leeman, J.R., McNeil, C., Taylor, W.P., Memmott, C., Jiang, M., Rijnbrand, R., Bral, C., Germann, U., Nezami, A., Zhang, Y., Salituro, F.G., Bennani, Y.L., Charifson, P.S. J.Med.Chem.
Header	Transcription/Transcription Inhibitor
Released	2013-10-24
Resolution	2.820
CATH Insert Date	10 Aug, 2014

PDB Images (3)

Image of CATH 4ncm

4ncm

PDB 4ncm

Image of CATH 4ncmA

4ncmA

PDB Chain 4ncmA

Image of CATH 4ncmA00

4ncmA00

CATH Domain 4ncmA00

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	11 Aug, 2014	Chopped

CATH Domains (1)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4ncmA00	20 Aug, 2014		Holding pen

UniProtKB Entries (1)

Accession	Gene ID	Taxon	Description
P31345	PB2_I75A3	Influenza A virus (A/Victoria/3/1975(H3N2))	Polymerase basic protein 2