PDB 4n6y

PDB Information

PDB4N6Y
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure Guided Optimization, in Vitro Activity, and in Vivo Activity of Pan-PIM Kinase Inhibitors.
Burger, M.T., Han, W., Lan, J., Nishiguchi, G., Bellamacina, C., Lindval, M., Atallah, G., Ding, Y., Mathur, M., McBride, C., Beans, E.L., Muller, K., Tamez, V., Zhang, Y., Huh, K., Feucht, P., Zavorotinskaya, T., Dai, Y., Holash, J., Castillo, J., Langowski, J., Wang, Y., Chen, M.Y., Garcia, P.D.
ACS Med Chem Lett
HeaderTransferase/Transferase Inhibitor
Released2013-10-14
Resolution2.600
CATH Insert Date10 Nov, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 11 Nov, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4n6yA01 13 Nov, 2013 3.30.200.20 Assigned
4n6yA02 13 Nov, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P11309 PIM1_HUMAN Homo sapiens Serine/threonine-protein kinase pim-1