PDB 4mro

PDB Information

PDB4MRO
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Small molecule disruptors of the glucokinase-glucokinase regulatory protein interaction: 2. Leveraging structure-based drug design to identify analogues with improved pharmacokinetic profiles.
St Jean, D.J., Ashton, K.S., Bartberger, M.D., Chen, J., Chmait, S., Cupples, R., Galbreath, E., Helmering, J., Hong, F.T., Jordan, S.R., Liu, L., Kunz, R.K., Michelsen, K., Nishimura, N., Pennington, L.D., Poon, S.F., Reid, D., Sivits, G., Stec, M.M., Tadesse, S., Tamayo, N., Van, G., Yang, K.C., Zhang, J., Norman, M.H., Fotsch, C., Lloyd, D.J., Hale, C.
J.Med.Chem.
HeaderTransferase Inhibitor
Released2013-09-17
Resolution2.200
CATH Insert Date11 May, 2014

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 12 May, 2014 Chopped
B 12 May, 2014 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4mroA01 17 May, 2014 3.40.50.10490 Assigned
4mroA02 17 May, 2014 Holding pen
4mroA03 17 May, 2014 Holding pen
4mroB01 17 May, 2014 3.40.50.10490 Assigned
4mroB02 17 May, 2014 Holding pen
4mroB03 17 May, 2014 Holding pen

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q14397 GCKR_HUMAN Homo sapiens Glucokinase regulatory protein
Q14397 GCKR_HUMAN Homo sapiens Glucokinase regulatory protein