PDB Information

PDB4LYN
MethodX-RAY DIFFRACTION
Host OrganismESCHERICHIA COLI
Gene SourceHomo sapiens
Primary Citation
Discovery of Aminothiazole Inhibitors of Cyclin-Dependent Kinase 2: Synthesis, X-Ray Crystallographic Analysis, and Biological Activities
Kim, K.S., Kimball, S.D., Misra, R.N., Rawlins, D.B., Hunt, J.T., Xiao, H.-Y., Lu, S., Qian, L., Han, W.C., Shan, W., Mitt, T., Cai, Z.-W., Poss, M.A., Zhu, H., Sack, J.S., Tokarski, J.S., Chang, C.Y., Pavletich, N., Kamath, A., Humphreys, W.G., Marathe, P., Bursuker, I., Kellar, K.A., Roongta, U., Batorsky, R., Mulheron, J.G., Bol, D., Fairchild, C.R., Lee, F.Y., Webster, K.R.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-07-31
Resolution2.000
CATH Insert Date06 Oct, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4lynA01 10 Oct, 2013 3.30.200.20 Assigned
4lynA02 10 Oct, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P24941 CDK2_HUMAN Homo sapiens Cyclin-dependent kinase 2