PDB 4l53

PDB Links
Overview

PDB Information

PDB	4L53
Method	X-RAY DIFFRACTION
Host Organism	Spodoptera frugiperda
Gene Source	Homo sapiens
Primary Citation	Discovery of 7-aminofuro[2,3-c]pyridine inhibitors of TAK1: Optimization of kinase selectivity and pharmacokinetics. Hornberger, K.R., Chen, X., Crew, A.P., Kleinberg, A., Ma, L., Mulvihill, M.J., Wang, J., Wilde, V.L., Albertella, M., Bittner, M., Cooke, A., Kadhim, S., Kahler, J., Maresca, P., May, E., Meyn, P., Romashko, D., Tokar, B., Turton, R. Bioorg.Med.Chem.Lett.
Header	Transferase/Transferase Inhibitor
Released	2013-06-10
Resolution	2.550
CATH Insert Date	04 Aug, 2013

PDB Images (4)

Image of CATH 4l53

4l53

PDB 4l53

Image of CATH 4l53A

4l53A

PDB Chain 4l53A

Image of CATH 4l53A01

4l53A01

CATH Domain 4l53A01

Image of CATH 4l53A02

4l53A02

CATH Domain 4l53A02

PDB Prints

PDB Chains (1)

Chain ID	Date inserted into CATH	CATH Status
A	05 Aug, 2013	Chopped

CATH Domains (2)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4l53A01	14 Aug, 2013	3.30.200.20	Assigned
4l53A02	14 Aug, 2013	1.10.510.10	Assigned

UniProtKB Entries (2)

Accession	Gene ID	Taxon	Description
O43318	M3K7_HUMAN	Homo sapiens	Mitogen-activated protein kinase kinase kinase 7
Q15750	TAB1_HUMAN	Homo sapiens	TGF-beta-activated kinase 1 and MAP3K7-binding protein 1