PDB 4l3o

PDB Information

PDB4L3O
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structural Basis for Potent Inhibition of SIRT2 Deacetylase by a Macrocyclic Peptide Inducing Dynamic Structural Change
Yamagata, K., Goto, Y., Nishimasu, H., Morimoto, J., Ishitani, R., Dohmae, N., Takeda, N., Nagai, R., Komuro, I., Suga, H., Nureki, O.
Structure
HeaderHydrolase/Hydrolase Inhibitor
Released2013-06-06
Resolution2.520
CATH Insert Date23 Feb, 2014

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 24 Feb, 2014 Chopped
B 24 Feb, 2014 Chopped
C 24 Feb, 2014 Chopped
D 24 Feb, 2014 Chopped
E 24 Feb, 2014 Rejected
F 24 Feb, 2014 Rejected
G 24 Feb, 2014 Rejected
H 24 Feb, 2014 Rejected

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4l3oA01 07 Mar, 2014 3.40.50.1220 Assigned
4l3oA02 07 Mar, 2014 3.30.1600.10 Assigned
4l3oB01 07 Mar, 2014 3.40.50.1220 Assigned
4l3oB02 07 Mar, 2014 3.30.1600.10 Assigned
4l3oC01 07 Mar, 2014 3.40.50.1220 Assigned
4l3oC02 07 Mar, 2014 3.30.1600.10 Assigned
4l3oD01 07 Mar, 2014 3.40.50.1220 Assigned
4l3oD02 07 Mar, 2014 3.30.1600.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2
Q8IXJ6 SIR2_HUMAN Homo sapiens NAD-dependent protein deacetylase sirtuin-2