PDB 4kzl

PDB Links
Overview

PDB Information

PDB	4KZL
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. Narwal, M., Koivunen, J., Haikarainen, T., Obaji, E., Legala, O.E., Venkannagari, H., Joensuu, P., Pihlajaniemi, T., Lehtio, L. J.Med.Chem.
Header	Transferase/Transferase Inhibitor
Released	2013-05-30
Resolution	2.000
CATH Insert Date	03 Nov, 2013

PDB Images (9)

Image of CATH 4kzl

4kzl

PDB 4kzl

Image of CATH 4kzlA

4kzlA

PDB Chain 4kzlA

Image of CATH 4kzlB

4kzlB

PDB Chain 4kzlB

Image of CATH 4kzlC

4kzlC

PDB Chain 4kzlC

Image of CATH 4kzlD

4kzlD

PDB Chain 4kzlD

Image of CATH 4kzlA00

4kzlA00

CATH Domain 4kzlA00

Image of CATH 4kzlB00

4kzlB00

CATH Domain 4kzlB00

Image of CATH 4kzlC00

4kzlC00

CATH Domain 4kzlC00

Image of CATH 4kzlD00

4kzlD00

CATH Domain 4kzlD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	04 Nov, 2013	Chopped
B	04 Nov, 2013	Chopped
C	04 Nov, 2013	Chopped
D	04 Nov, 2013	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kzlA00	08 Nov, 2013	3.90.228.10	Assigned
4kzlB00	08 Nov, 2013	3.90.228.10	Assigned
4kzlC00	08 Nov, 2013	6.20.320.10	Assigned
4kzlD00	08 Nov, 2013	6.20.320.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2
Q9H2K2	TNKS2_HUMAN	Homo sapiens	Poly [ADP-ribose] polymerase tankyrase-2