PDB 4kwg

PDB Links
Overview

PDB Information

PDB	4KWG
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Development of selective inhibitors for aldehyde dehydrogenases based on substituted indole-2,3-diones. Kimble-Hill, A.C., Parajuli, B., Chen, C.H., Mochly-Rosen, D., Hurley, T.D. J.Med.Chem.
Header	Oxidoreductase/Inhibitor
Released	2013-05-24
Resolution	2.100
CATH Insert Date	13 Apr, 2014

PDB Images (25)

4kwg

PDB 4kwg

4kwgA

PDB Chain 4kwgA

4kwgB

PDB Chain 4kwgB

4kwgC

PDB Chain 4kwgC

4kwgD

PDB Chain 4kwgD

4kwgE

PDB Chain 4kwgE

4kwgF

PDB Chain 4kwgF

4kwgG

PDB Chain 4kwgG

4kwgH

PDB Chain 4kwgH

4kwgA01

CATH Domain 4kwgA01

4kwgA02

CATH Domain 4kwgA02

4kwgB01

CATH Domain 4kwgB01

4kwgB02

CATH Domain 4kwgB02

4kwgC01

CATH Domain 4kwgC01

4kwgC02

CATH Domain 4kwgC02

4kwgD01

CATH Domain 4kwgD01

4kwgD02

CATH Domain 4kwgD02

4kwgE01

CATH Domain 4kwgE01

4kwgE02

CATH Domain 4kwgE02

4kwgF01

CATH Domain 4kwgF01

4kwgF02

CATH Domain 4kwgF02

4kwgG01

CATH Domain 4kwgG01

4kwgG02

CATH Domain 4kwgG02

4kwgH01

CATH Domain 4kwgH01

4kwgH02

CATH Domain 4kwgH02

PDB Prints

PDB Chains (8)

Chain ID	Date inserted into CATH	CATH Status
A	14 Apr, 2014	Chopped
B	14 Apr, 2014	Chopped
C	14 Apr, 2014	Chopped
D	14 Apr, 2014	Chopped
E	14 Apr, 2014	Chopped
F	14 Apr, 2014	Chopped
G	14 Apr, 2014	Chopped
H	14 Apr, 2014	Chopped

CATH Domains (16)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kwgA01	25 Apr, 2014	3.40.605.10	Assigned
4kwgA02	25 Apr, 2014	3.40.309.10	Assigned
4kwgB01	25 Apr, 2014	3.40.605.10	Assigned
4kwgB02	25 Apr, 2014	3.40.309.10	Assigned
4kwgC01	25 Apr, 2014	3.40.605.10	Assigned
4kwgC02	25 Apr, 2014	3.40.309.10	Assigned
4kwgD01	25 Apr, 2014	3.40.605.10	Assigned
4kwgD02	25 Apr, 2014	3.40.309.10	Assigned
4kwgE01	25 Apr, 2014	3.40.605.10	Assigned
4kwgE02	25 Apr, 2014	3.40.309.10	Assigned
4kwgF01	25 Apr, 2014	3.40.605.10	Assigned
4kwgF02	25 Apr, 2014	3.40.309.10	Assigned
4kwgG01	25 Apr, 2014	3.40.605.10	Assigned
4kwgG02	25 Apr, 2014	3.40.309.10	Assigned
4kwgH01	25 Apr, 2014	3.40.605.10	Assigned
4kwgH02	25 Apr, 2014	3.40.309.10	Assigned

UniProtKB Entries (8)

Accession	Gene ID	Taxon	Description
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial
P05091	ALDH2_HUMAN	Homo sapiens	Aldehyde dehydrogenase, mitochondrial