PDB 4kv5

PDB Links
Overview

PDB Information

PDB	4KV5
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	Structures of a pan-specific antagonist antibody complexed to different isoforms of TGF beta reveal structural plasticity of antibody-antigen interactions. Moulin, A., Mathieu, M., Lawrence, C., Bigelow, R., Levine, M., Hamel, C., Marquette, J.P., Le Parc, J., Loux, C., Ferrari, P., Capdevila, C., Dumas, J., Dumas, B., Rak, A., Bird, J., Qiu, H., Pan, C.Q., Edmunds, T., Wei, R.R. Protein Sci.
Header	Immune System
Released	2013-05-22
Resolution	3.000
CATH Insert Date	05 Oct, 2014

PDB Images (25)

4kv5

PDB 4kv5

4kv5A

PDB Chain 4kv5A

4kv5B

PDB Chain 4kv5B

4kv5C

PDB Chain 4kv5C

4kv5D

PDB Chain 4kv5D

4kv5E

PDB Chain 4kv5E

4kv5F

PDB Chain 4kv5F

4kv5G

PDB Chain 4kv5G

4kv5H

PDB Chain 4kv5H

4kv5I

PDB Chain 4kv5I

4kv5J

PDB Chain 4kv5J

4kv5K

PDB Chain 4kv5K

4kv5L

PDB Chain 4kv5L

4kv5A00

CATH Domain 4kv5A00

4kv5B00

CATH Domain 4kv5B00

4kv5C00

CATH Domain 4kv5C00

4kv5D00

CATH Domain 4kv5D00

4kv5E00

CATH Domain 4kv5E00

4kv5F00

CATH Domain 4kv5F00

4kv5G00

CATH Domain 4kv5G00

4kv5H00

CATH Domain 4kv5H00

4kv5I00

CATH Domain 4kv5I00

4kv5J00

CATH Domain 4kv5J00

4kv5K00

CATH Domain 4kv5K00

4kv5L00

CATH Domain 4kv5L00

PDB Prints

PDB Chains (12)

Chain ID	Date inserted into CATH	CATH Status
A	06 Oct, 2014	Chopped
B	06 Oct, 2014	Chopped
C	06 Oct, 2014	Chopped
D	06 Oct, 2014	Chopped
E	06 Oct, 2014	Chopped
F	06 Oct, 2014	Chopped
G	06 Oct, 2014	Chopped
H	06 Oct, 2014	Chopped
I	06 Oct, 2014	Chopped
J	06 Oct, 2014	Chopped
K	06 Oct, 2014	Chopped
L	06 Oct, 2014	Chopped

CATH Domains (12)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4kv5A00	08 Oct, 2014	2.10.90.10	Assigned
4kv5B00	07 Oct, 2014	2.10.90.10	Assigned
4kv5C00	08 Oct, 2014	2.10.90.10	Assigned
4kv5D00	08 Oct, 2014	2.10.90.10	Assigned
4kv5E00	07 Oct, 2014	2.60.40.10	Assigned
4kv5F00	08 Oct, 2014	2.60.40.10	Assigned
4kv5G00	08 Oct, 2014	2.60.40.10	Assigned
4kv5H00	08 Oct, 2014	2.60.40.10	Assigned
4kv5I00	07 Oct, 2014	2.60.40.10	Assigned
4kv5J00	08 Oct, 2014	2.60.40.10	Assigned
4kv5K00	08 Oct, 2014	2.60.40.10	Assigned
4kv5L00	08 Oct, 2014	2.60.40.10	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P01137	TGFB1_HUMAN	Homo sapiens	Transforming growth factor beta-1 proprotein
P01137	TGFB1_HUMAN	Homo sapiens	Transforming growth factor beta-1 proprotein
P01137	TGFB1_HUMAN	Homo sapiens	Transforming growth factor beta-1 proprotein
P01137	TGFB1_HUMAN	Homo sapiens	Transforming growth factor beta-1 proprotein

Network disruptions