PDB Information

PDB4KP7
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourcePlasmodium falciparum
Primary Citation
IspC as Target for Antiinfective Drug Discovery: Synthesis, Enantiomeric Separation, and Structural Biology of Fosmidomycin Thia Isosters.
Kunfermann, A., Lienau, C., Illarionov, B., Held, J., Grawert, T., Behrendt, C.T., Werner, P., Hahn, S., Eisenreich, W., Riederer, U., Mordmuller, B., Bacher, A., Fischer, M., Groll, M., Kurz, T.
J.Med.Chem.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2013-05-13
Resolution2.000
CATH Insert Date06 Oct, 2013

PDB Images (9)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 07 Oct, 2013 Chopped
B 07 Oct, 2013 Chopped

CATH Domains (6)

Domain ID Date inserted into CATH Superfamily CATH Status
4kp7A01 10 Oct, 2013 3.40.50.720 Assigned
4kp7A02 10 Oct, 2013 Holding pen
4kp7A03 10 Oct, 2013 1.10.1740.10 Assigned
4kp7B01 10 Oct, 2013 3.40.50.720 Assigned
4kp7B02 10 Oct, 2013 Holding pen
4kp7B03 10 Oct, 2013 1.10.1740.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O96693 DXR_PLAFX Plasmodium falciparum HB3 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic
O96693 DXR_PLAFX Plasmodium falciparum HB3 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic