PDB 4kfo

PDB Information

PDB4KFO
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Structure-based identification of ureas as novel nicotinamide phosphoribosyltransferase (nampt) inhibitors.
Zheng, X., Bauer, P., Baumeister, T., Buckmelter, A.J., Caligiuri, M., Clodfelter, K.H., Han, B., Ho, Y.C., Kley, N., Lin, J., Reynolds, D.J., Sharma, G., Smith, C.C., Wang, Z., Dragovich, P.S., Oh, A., Wang, W., Zak, M., Gunzner-Toste, J., Zhao, G., Yuen, P.W., Bair, K.W.
J.Med.Chem.
HeaderTransferase/Transferase Inhibitor
Released2013-04-27
Resolution1.600
CATH Insert Date07 Jul, 2013

PDB Images (7)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 08 Jul, 2013 Chopped
B 08 Jul, 2013 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
4kfoA01 09 Aug, 2013 Holding pen
4kfoA02 09 Aug, 2013 3.20.20.70 Assigned
4kfoB01 09 Aug, 2013 Holding pen
4kfoB02 09 Aug, 2013 3.20.20.70 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P43490 NAMPT_HUMAN Homo sapiens Nicotinamide phosphoribosyltransferase
P43490 NAMPT_HUMAN Homo sapiens Nicotinamide phosphoribosyltransferase