PDB 4k1l

PDB Links
Overview

PDB Information

PDB	4K1L
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli
Gene Source	Homo sapiens
Primary Citation	1,1-Dioxo-5,6-dihydro-[4,1,2]oxathiazines, a novel class of 11-HSD1 inhibitors for the treatment of diabetes. Bohme, T., Engel, C.K., Farjot, G., Gussregen, S., Haack, T., Tschank, G., Ritter, K. Bioorg.Med.Chem.Lett.
Header	Oxidoreductase/Oxidoreductase Inhibitor
Released	2013-04-05
Resolution	1.960
CATH Insert Date	13 Apr, 2014

PDB Images (9)

Image of CATH 4k1l

4k1l

PDB 4k1l

Image of CATH 4k1lA

4k1lA

PDB Chain 4k1lA

Image of CATH 4k1lB

4k1lB

PDB Chain 4k1lB

Image of CATH 4k1lC

4k1lC

PDB Chain 4k1lC

Image of CATH 4k1lD

4k1lD

PDB Chain 4k1lD

Image of CATH 4k1lA00

4k1lA00

CATH Domain 4k1lA00

Image of CATH 4k1lB00

4k1lB00

CATH Domain 4k1lB00

Image of CATH 4k1lC00

4k1lC00

CATH Domain 4k1lC00

Image of CATH 4k1lD00

4k1lD00

CATH Domain 4k1lD00

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	14 Apr, 2014	Chopped
B	14 Apr, 2014	Chopped
C	14 Apr, 2014	Chopped
D	14 Apr, 2014	Chopped

CATH Domains (4)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
4k1lA00	17 Apr, 2014	3.40.50.720	Assigned
4k1lB00	25 Apr, 2014	3.40.50.720	Assigned
4k1lC00	25 Apr, 2014	3.40.50.720	Assigned
4k1lD00	25 Apr, 2014	3.40.50.720	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1
P28845	DHI1_HUMAN	Homo sapiens	Corticosteroid 11-beta-dehydrogenase isozyme 1