PDB 4joa

PDB Information

PDB4JOA
MethodX-RAY DIFFRACTION
Host OrganismSpodoptera frugiperda
Gene SourceHomo sapiens
Primary Citation
Discovery of 7-azaindole based anaplastic lymphoma kinase (ALK) inhibitors: wild type and mutant (L1196M) active compounds with unique binding mode
Gummadi, V.R., Rajagopalan, S., Looi, C.Y., Paydar, M., Renukappa, G.A., Ainan, B.R., Krishnamurthy, N.R., Panigrahi, S.K., Mahasweta, K., Raghuramachandran, S., Rajappa, M., Ramanathan, A., Lakshminarasimhan, A., Ramachandra, M., Wong, P.F., Mustafa, M.R., Nanduri, S., Hosahalli, S.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-03-18
Resolution2.700
CATH Insert Date04 Aug, 2013

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Aug, 2013 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4joaA01 14 Aug, 2013 3.30.200.20 Assigned
4joaA02 14 Aug, 2013 1.10.510.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
Q9UM73 ALK_HUMAN Homo sapiens ALK tyrosine kinase receptor