PDB 4j8n

PDB Information

PDB4J8N
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Drugging MYCN through an Allosteric Transition in Aurora Kinase A.
Gustafson, W.C., Meyerowitz, J.G., Nekritz, E.A., Chen, J., Benes, C., Charron, E., Simonds, E.F., Seeger, R., Matthay, K.K., Hertz, N.T., Eilers, M., Shokat, K.M., Weiss, W.A.
Cancer Cell
HeaderTransferase
Released2013-02-14
Resolution3.140
CATH Insert Date14 Sep, 2014

PDB Images (13)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 15 Sep, 2014 Chopped
B 15 Sep, 2014 Chopped
C 15 Sep, 2014 Chopped
D 15 Sep, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4j8nA01 16 Sep, 2014 3.30.200.20 Assigned
4j8nA02 16 Sep, 2014 1.10.510.10 Assigned
4j8nB01 16 Sep, 2014 3.30.200.20 Assigned
4j8nB02 16 Sep, 2014 1.10.510.10 Assigned
4j8nC01 16 Sep, 2014 3.30.200.20 Assigned
4j8nC02 16 Sep, 2014 1.10.510.10 Assigned
4j8nD01 16 Sep, 2014 3.30.200.20 Assigned
4j8nD02 16 Sep, 2014 1.10.510.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A
O14965 AURKA_HUMAN Homo sapiens Aurora kinase A