PDB 4j4t

PDB Information

PDB4J4T
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceFrancisella tularensis subsp. tularensis
Primary Citation
Structural and biological evaluation of a novel series of benzimidazole inhibitors of Francisella tularensis enoyl-ACP reductase (FabI).
Mehboob, S., Song, J., Hevener, K.E., Su, P.C., Boci, T., Brubaker, L., Truong, L., Mistry, T., Deng, J., Cook, J.L., Santarsiero, B.D., Ghosh, A.K., Johnson, M.E.
Bioorg.Med.Chem.Lett.
HeaderOxidoreductase/Oxidoreductase Inhibitor
Released2013-02-07
Resolution2.340
CATH Insert Date10 Aug, 2014

PDB Images (17)

PDB Prints

PDB Chains (8)

Chain ID Date inserted into CATH CATH Status
A 11 Aug, 2014 Chopped
B 11 Aug, 2014 Chopped
C 11 Aug, 2014 Chopped
D 11 Aug, 2014 Chopped
E 11 Aug, 2014 Chopped
F 11 Aug, 2014 Chopped
G 11 Aug, 2014 Chopped
H 11 Aug, 2014 Chopped

CATH Domains (8)

Domain ID Date inserted into CATH Superfamily CATH Status
4j4tA00 20 Aug, 2014 3.40.50.720 Assigned
4j4tB00 20 Aug, 2014 3.40.50.720 Assigned
4j4tC00 20 Aug, 2014 3.40.50.720 Assigned
4j4tD00 20 Aug, 2014 3.40.50.720 Assigned
4j4tE00 20 Aug, 2014 3.40.50.720 Assigned
4j4tF00 20 Aug, 2014 3.40.50.720 Assigned
4j4tG00 20 Aug, 2014 3.40.50.720 Assigned
4j4tH00 20 Aug, 2014 3.40.50.720 Assigned

UniProtKB Entries (8)

Accession Gene ID Taxon Description
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]
Q5NGQ3 Q5NGQ3_FRATT Francisella tularensis subsp. tularensis SCHU S4 Enoyl-[acyl-carrier-protein] reductase [NADH]