PDB 4j23

PDB Information

PDB4J23
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Molecular mechanism of SSR128129E, an extracellularly acting, small-molecule, allosteric inhibitor of FGF receptor signaling.
Herbert, C., Schieborr, U., Saxena, K., Juraszek, J., De Smet, F., Alcouffe, C., Bianciotto, M., Saladino, G., Sibrac, D., Kudlinzki, D., Sreeramulu, S., Brown, A., Rigon, P., Herault, J.P., Lassalle, G., Blundell, T.L., Rousseau, F., Gils, A., Schymkowitz, J., Tompa, P., Herbert, J.M., Carmeliet, P., Gervasio, F.L., Schwalbe, H., Bono, F.
Cancer Cell
HeaderSignaling Protein/Transferase
Released2013-02-04
Resolution3.880
CATH Insert Date23 Feb, 2014

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 24 Feb, 2014 Chopped
B 24 Feb, 2014 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4j23A01 07 Mar, 2014 2.60.40.10 Assigned
4j23A02 07 Mar, 2014 2.60.40.10 Assigned
4j23B00 07 Mar, 2014 2.80.10.50 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P05230 FGF1_HUMAN Homo sapiens Fibroblast growth factor 1
P21802 FGFR2_HUMAN Homo sapiens Fibroblast growth factor receptor 2