PDB 4izy

PDB Information

PDB4IZY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Development of indole/indazole-aminopyrimidines as inhibitors of c-Jun N-terminal kinase (JNK): optimization for JNK potency and physicochemical properties.
Gong, L., Han, X., Silva, T., Tan, Y.C., Goyal, B., Tivitmahaisoon, P., Trejo, A., Palmer, W., Hogg, H., Jahagir, A., Alam, M., Wagner, P., Stein, K., Filonova, L., Loe, B., Makra, F., Rotstein, D., Rapatova, L., Dunn, J., Zuo, F., Dal Porto, J., Wong, B., Jin, S., Chang, A., Tran, P., Hsieh, G., Niu, L., Shao, A., Reuter, D., Hermann, J., Kuglstatter, A., Goldstein, D.
Bioorg.Med.Chem.Lett.
HeaderTransferase/Transferase Inhibitor
Released2013-01-30
Resolution2.300
CATH Insert Date22 Dec, 2013

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 23 Dec, 2013 Chopped
B 23 Dec, 2013 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
4izyA01 26 Dec, 2013 3.30.200.20 Assigned
4izyA02 26 Dec, 2013 1.10.510.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
Q9UQF2 JIP1_HUMAN Homo sapiens C-Jun-amino-terminal kinase-interacting protein 1
P45983 MK08_HUMAN Homo sapiens Mitogen-activated protein kinase 8