PDB 4isi

PDB Information

PDB4ISI
MethodX-RAY DIFFRACTION
Host OrganismCricetinae
Gene SourceHomo sapiens
Primary Citation
Design and synthesis of bicyclic pyrazinone and pyrimidinone amides as potent TF-FVIIa inhibitors.
Zhang, X., Glunz, P.W., Jiang, W., Schmitt, A., Newman, M., Barbera, F.A., Bozarth, J.M., Rendina, A.R., Wei, A., Wen, X., Rossi, K.A., Luettgen, J.M., Wong, P.C., Knabb, R.M., Wexler, R.R., Scott Priestley, E.
Bioorg.Med.Chem.Lett.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-01-16
Resolution1.940
CATH Insert Date28 Mar, 2013

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
H 28 Mar, 2013 Chopped
L 28 Mar, 2013 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
4isiH01 10 Apr, 2013 2.40.10.10 Assigned
4isiH02 10 Apr, 2013 2.40.10.10 Assigned
4isiL00 10 Apr, 2013 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII
P08709 FA7_HUMAN Homo sapiens Coagulation factor VII