PDB Information

PDB4INU
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites.
Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E., Voges, M.J., Mock, E.D., Florea, B.I., van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-01-06
Resolution3.100
CATH Insert Date03 Feb, 2013

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 04 Feb, 2013 Chopped
A 04 Feb, 2013 Chopped
b 04 Feb, 2013 Chopped
B 04 Feb, 2013 Chopped
C 04 Feb, 2013 Chopped
D 04 Feb, 2013 Chopped
E 04 Feb, 2013 Chopped
F 04 Feb, 2013 Chopped
G 04 Feb, 2013 Chopped
H 04 Feb, 2013 Chopped
I 04 Feb, 2013 Chopped
J 04 Feb, 2013 Chopped
K 04 Feb, 2013 Chopped
L 04 Feb, 2013 Chopped
M 04 Feb, 2013 Chopped
N 04 Feb, 2013 Chopped
O 04 Feb, 2013 Chopped
P 04 Feb, 2013 Chopped
Q 04 Feb, 2013 Chopped
R 04 Feb, 2013 Chopped
S 04 Feb, 2013 Chopped
T 04 Feb, 2013 Chopped
U 04 Feb, 2013 Chopped
V 04 Feb, 2013 Chopped
W 04 Feb, 2013 Chopped
X 04 Feb, 2013 Chopped
Y 04 Feb, 2013 Chopped
Z 04 Feb, 2013 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
4inua00 11 Feb, 2013 3.60.20.10 Assigned
4inuA00 11 Feb, 2013 3.60.20.10 Assigned
4inub00 11 Feb, 2013 3.60.20.10 Assigned
4inuB00 11 Feb, 2013 3.60.20.10 Assigned
4inuC00 11 Feb, 2013 3.60.20.10 Assigned
4inuD00 11 Feb, 2013 3.60.20.10 Assigned
4inuE00 11 Feb, 2013 3.60.20.10 Assigned
4inuF00 11 Feb, 2013 3.60.20.10 Assigned
4inuG00 11 Feb, 2013 3.60.20.10 Assigned
4inuH00 11 Feb, 2013 3.60.20.10 Assigned
4inuI00 11 Feb, 2013 3.60.20.10 Assigned
4inuJ00 11 Feb, 2013 3.60.20.10 Assigned
4inuK00 11 Feb, 2013 3.60.20.10 Assigned
4inuL00 11 Feb, 2013 3.60.20.10 Assigned
4inuM00 11 Feb, 2013 3.60.20.10 Assigned
4inuN00 11 Feb, 2013 3.60.20.10 Assigned
4inuO00 11 Feb, 2013 3.60.20.10 Assigned
4inuP00 11 Feb, 2013 3.60.20.10 Assigned
4inuQ00 11 Feb, 2013 3.60.20.10 Assigned
4inuR00 11 Feb, 2013 3.60.20.10 Assigned
4inuS00 11 Feb, 2013 3.60.20.10 Assigned
4inuT00 11 Feb, 2013 3.60.20.10 Assigned
4inuU00 11 Feb, 2013 3.60.20.10 Assigned
4inuV00 11 Feb, 2013 3.60.20.10 Assigned
4inuW00 11 Feb, 2013 3.60.20.10 Assigned
4inuX00 11 Feb, 2013 3.60.20.10 Assigned
4inuY00 11 Feb, 2013 3.60.20.10 Assigned
4inuZ00 11 Feb, 2013 3.60.20.10 Assigned

UniProtKB Entries (28)

Accession Gene ID Taxon Description
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1