PDB Information

PDB4INT
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites.
Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E., Voges, M.J., Mock, E.D., Florea, B.I., van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-01-06
Resolution2.900
CATH Insert Date03 Feb, 2013

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 04 Feb, 2013 Chopped
A 04 Feb, 2013 Chopped
b 04 Feb, 2013 Chopped
B 04 Feb, 2013 Chopped
C 04 Feb, 2013 Chopped
D 04 Feb, 2013 Chopped
E 04 Feb, 2013 Chopped
F 04 Feb, 2013 Chopped
G 04 Feb, 2013 Chopped
H 04 Feb, 2013 Chopped
I 04 Feb, 2013 Chopped
J 04 Feb, 2013 Chopped
K 04 Feb, 2013 Chopped
L 04 Feb, 2013 Chopped
M 04 Feb, 2013 Chopped
N 04 Feb, 2013 Chopped
O 04 Feb, 2013 Chopped
P 04 Feb, 2013 Chopped
Q 04 Feb, 2013 Chopped
R 04 Feb, 2013 Chopped
S 04 Feb, 2013 Chopped
T 04 Feb, 2013 Chopped
U 04 Feb, 2013 Chopped
V 04 Feb, 2013 Chopped
W 04 Feb, 2013 Chopped
X 04 Feb, 2013 Chopped
Y 04 Feb, 2013 Chopped
Z 04 Feb, 2013 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
4inta00 11 Feb, 2013 3.60.20.10 Assigned
4intA00 11 Feb, 2013 3.60.20.10 Assigned
4intb00 11 Feb, 2013 3.60.20.10 Assigned
4intB00 11 Feb, 2013 3.60.20.10 Assigned
4intC00 11 Feb, 2013 3.60.20.10 Assigned
4intD00 11 Feb, 2013 3.60.20.10 Assigned
4intE00 11 Feb, 2013 3.60.20.10 Assigned
4intF00 11 Feb, 2013 3.60.20.10 Assigned
4intG00 11 Feb, 2013 3.60.20.10 Assigned
4intH00 11 Feb, 2013 3.60.20.10 Assigned
4intI00 11 Feb, 2013 3.60.20.10 Assigned
4intJ00 11 Feb, 2013 3.60.20.10 Assigned
4intK00 11 Feb, 2013 3.60.20.10 Assigned
4intL00 11 Feb, 2013 3.60.20.10 Assigned
4intM00 11 Feb, 2013 3.60.20.10 Assigned
4intN00 11 Feb, 2013 3.60.20.10 Assigned
4intO00 11 Feb, 2013 3.60.20.10 Assigned
4intP00 11 Feb, 2013 3.60.20.10 Assigned
4intQ00 11 Feb, 2013 3.60.20.10 Assigned
4intR00 11 Feb, 2013 3.60.20.10 Assigned
4intS00 11 Feb, 2013 3.60.20.10 Assigned
4intT00 11 Feb, 2013 3.60.20.10 Assigned
4intU00 11 Feb, 2013 3.60.20.10 Assigned
4intV00 11 Feb, 2013 3.60.20.10 Assigned
4intW00 11 Feb, 2013 3.60.20.10 Assigned
4intX00 11 Feb, 2013 3.60.20.10 Assigned
4intY00 11 Feb, 2013 3.60.20.10 Assigned
4intZ00 11 Feb, 2013 3.60.20.10 Assigned

UniProtKB Entries (28)

Accession Gene ID Taxon Description
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4