PDB Information

PDB4INR
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Incorporation of Non-natural Amino Acids Improves Cell Permeability and Potency of Specific Inhibitors of Proteasome Trypsin-like Sites.
Geurink, P.P., van der Linden, W.A., Mirabella, A.C., Gallastegui, N., de Bruin, G., Blom, A.E., Voges, M.J., Mock, E.D., Florea, B.I., van der Marel, G.A., Driessen, C., van der Stelt, M., Groll, M., Overkleeft, H.S., Kisselev, A.F.
J.Med.Chem.
HeaderHydrolase/Hydrolase Inhibitor
Released2013-01-06
Resolution2.700
CATH Insert Date03 Feb, 2013

PDB Images (57)

PDB Prints

PDB Chains (28)

Chain ID Date inserted into CATH CATH Status
a 04 Feb, 2013 Chopped
A 04 Feb, 2013 Chopped
b 04 Feb, 2013 Chopped
B 04 Feb, 2013 Chopped
C 04 Feb, 2013 Chopped
D 04 Feb, 2013 Chopped
E 04 Feb, 2013 Chopped
F 04 Feb, 2013 Chopped
G 04 Feb, 2013 Chopped
H 04 Feb, 2013 Chopped
I 04 Feb, 2013 Chopped
J 04 Feb, 2013 Chopped
K 04 Feb, 2013 Chopped
L 04 Feb, 2013 Chopped
M 04 Feb, 2013 Chopped
N 04 Feb, 2013 Chopped
O 04 Feb, 2013 Chopped
P 04 Feb, 2013 Chopped
Q 04 Feb, 2013 Chopped
R 04 Feb, 2013 Chopped
S 04 Feb, 2013 Chopped
T 04 Feb, 2013 Chopped
U 04 Feb, 2013 Chopped
V 04 Feb, 2013 Chopped
W 04 Feb, 2013 Chopped
X 04 Feb, 2013 Chopped
Y 04 Feb, 2013 Chopped
Z 04 Feb, 2013 Chopped

CATH Domains (28)

Domain ID Date inserted into CATH Superfamily CATH Status
4inra00 11 Feb, 2013 3.60.20.10 Assigned
4inrA00 11 Feb, 2013 3.60.20.10 Assigned
4inrb00 11 Feb, 2013 3.60.20.10 Assigned
4inrB00 11 Feb, 2013 3.60.20.10 Assigned
4inrC00 11 Feb, 2013 3.60.20.10 Assigned
4inrD00 11 Feb, 2013 3.60.20.10 Assigned
4inrE00 11 Feb, 2013 3.60.20.10 Assigned
4inrF00 11 Feb, 2013 3.60.20.10 Assigned
4inrG00 11 Feb, 2013 3.60.20.10 Assigned
4inrH00 11 Feb, 2013 3.60.20.10 Assigned
4inrI00 11 Feb, 2013 3.60.20.10 Assigned
4inrJ00 11 Feb, 2013 3.60.20.10 Assigned
4inrK00 11 Feb, 2013 3.60.20.10 Assigned
4inrL00 11 Feb, 2013 3.60.20.10 Assigned
4inrM00 11 Feb, 2013 3.60.20.10 Assigned
4inrN00 11 Feb, 2013 3.60.20.10 Assigned
4inrO00 11 Feb, 2013 3.60.20.10 Assigned
4inrP00 11 Feb, 2013 3.60.20.10 Assigned
4inrQ00 11 Feb, 2013 3.60.20.10 Assigned
4inrR00 11 Feb, 2013 3.60.20.10 Assigned
4inrS00 11 Feb, 2013 3.60.20.10 Assigned
4inrT00 11 Feb, 2013 3.60.20.10 Assigned
4inrU00 11 Feb, 2013 3.60.20.10 Assigned
4inrV00 11 Feb, 2013 3.60.20.10 Assigned
4inrW00 11 Feb, 2013 3.60.20.10 Assigned
4inrX00 11 Feb, 2013 3.60.20.10 Assigned
4inrY00 11 Feb, 2013 3.60.20.10 Assigned
4inrZ00 11 Feb, 2013 3.60.20.10 Assigned

UniProtKB Entries (28)

Accession Gene ID Taxon Description
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P25043 PSB2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-2
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P22141 PSB4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-4
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P21243 PSA1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-1
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P23638 PSA3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-3
P40302 PSA6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-6
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P38624 PSB1_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-1
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P23724 PSB6_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-6
P40303 PSA4_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-4
P25451 PSB3_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-3
P30657 PSB7_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-7
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7
P32379 PSA5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-5
P30656 PSB5_YEAST Saccharomyces cerevisiae S288C Proteasome subunit beta type-5
P23639 PSA2_YEAST Saccharomyces cerevisiae S288C Proteasome subunit alpha type-2
P21242 PSA7_YEAST Saccharomyces cerevisiae S288C Probable proteasome subunit alpha type-7